Simvastatin acid-d9 ammonium is deuterated labeled Simvastatin acid ammonium (HY-119695A). Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
Molecular Weight:
448.64
Formula:
C24H32D9NO6
Target:
HMG-CoA Reductase (HMGCR),Isotope-Labeled Compounds,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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