PV1115 is a potent and highly selective Chk2 inhibitor with an IC50 of 0.14 nM, 66000 nM, >100000 nM for Chk2, Chk1 and RSK2, respectively. PV1115 is situated within the ATP-binding pocket of Chk2[1].
Molecular Weight:
405.41
CAS Number:
[1093793-10-2]
Formula:
C20H19N7O3
Target:
Checkpoint Kinase (Chk)
Application Notes:
MCE Product type: Reference compound1
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