Barbadin is a novel and selective beta-arrestin/beta2-adaptin interaction inhibitor, has IC50 values of 19.1 µM for beta-arrestin1 and 15.6 µM for beta-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical beta2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis[1][2].
Molecular Weight:
333.41
Purity:
98.93
CAS Number:
[356568-70-2]
Formula:
C19H15N3OS
Target:
Apoptosis,Arrestin
Application Notes:
MCE Product type: Reference compound
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