Fosmanogepix (APX001) is a broad-spectrum agent against invasive fungal infections. Fosmanogepix (APX001) targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. This inhibition prevents the appropriate localization of cell wall mannoproteins, which compromises cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix (APX001) can be used for invasive fungal infections research[1].
Molecular Weight:
468.40
Purity:
97
CAS Number:
[2091769-17-2]
Formula:
C22H21N4O6P
Target:
Fungal
Application Notes:
MCE Product type: Reference compound1
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