AGK7 is a potent inhibitor of sirtuin 2 (SIRT2). AGK7 rescues alpha-synuclein toxicity and modified inclusion morphology in a cellular model of Parkinsons disease. AGK7 protects against dopaminergic cell death both in vitro and in a Drosophila model of Parkinsons disease[1].
Molecular Weight:
434.27
CAS Number:
[304896-21-7]
Formula:
C23H13Cl2N3O2
Target:
Sirtuin
Application Notes:
MCE Product type: Reference compound
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