ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2, with IC50 values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with IC50 of 75 nM. ROCK inhibitor-2 exhibits antitumor activity[1][2].
Molecular Weight:
332.40
Purity:
99.92
CAS Number:
[1127308-52-4]
Formula:
C21H20N2O2
Target:
ROCK
Application Notes:
MCE Product type: Reference compound
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