Cardanol monoene (Cardanol C15:1) is a phenolic compound which can be found in cashew nut shell liquid. Cardanol monoene can inhibit cancer cells proliferation, migration, cause S phase arrest, induce apoptosis, ROS production and mitochondrial depolarization. Cardanol monoene downregulates MMP-2, MMP-9, cyclinA1 expression, regulates CDK2, p53, Bax, cytochrome c, cleaved caspase-3, cleaved PARP, Apaf-1 expression and Bax/Bcl-2 ratio. Cardanol monoene shows weak DPPH radical scavenging activity and AChE inhibition activity. Cardanol monoene is lethal to Artemia salina nauplii. Cardanol monoene. Cardanol monoene can be used for the research of cancer, infection and inflamation[1][2].
Molecular Weight:
302.49
Purity:
98.02
CAS Number:
[501-26-8]
Formula:
C21H34O
Target:
Apoptosis,Bcl-2 Family,Caspase,CDK,Cholinesterase (ChE),MDM-2/p53,Mitochondrial Metabolism,MMP,PARP,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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