L-739749 is a farnesyl transferase inhibitor. L-739749 inhibits the selective hypersensitivity of JMML cells to granulocyte-macrophage colony-stimulating factor (GM-CSF) by blocking the prenylation of Ras. L-739749 exhibits a strong inhibitory effect on the growth of primary human JMML cells in vitro[1].
Molecular Weight:
531.73
CAS Number:
[156511-34-1]
Formula:
C24H41N3O6S2
Target:
Farnesyl Transferase,Ras
Application Notes:
MCE Product type: Reference compound1
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