DuP 747 hydrochloride is an analgesic with selective kappa-opioid receptor agonist activity. DuP 747 showed less spiradoline-appropriate selection when administered SC, but showed a partial generalized response to spiradoline when administered IP or PO. The 5-hydroxy-desmethoxy metabolite of DuP 747 induced selection of the saline-appropriate lever only. The effects of DuP 747 suggest that its metabolites may play a major role in the similar responses to spiradoline after IP and PO administration[1].
Molecular Weight:
483.86
CAS Number:
[115904-74-0]
Formula:
C24H29Cl3N2O2
Target:
Opioid Receptor
Application Notes:
MCE Product type: Reference compound
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