BTX161, a thalidomide analog, is an effective CKIalpha degrader. BTX161 mediates human AML cell CKIalpha degradation more effectively than lenalidomide and activates the DNA damage response (DDR) and p53, while stabilizing p53 antagonist MDM2.
Molecular Weight:
272.30
Purity:
99.20
CAS Number:
[2052301-24-1]
Formula:
C15H16N2O3
Target:
Casein Kinase
Application Notes:
MCE Product type: Reference compound1
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