OAT-177 is a potent dual inhibitor targeting acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with an IC50=14.2 nM for human AMCase and IC50=232 nM for human CHIT1. OAT-177 is promising for research of chronic inflammatory and fibrotic-related lung diseases such as asthma and idiopathic pulmonary fibrosis[1].
Molecular Weight:
376.93
CAS Number:
[1799548-33-6]
Formula:
C19H29ClN6
Target:
Parasite
Application Notes:
MCE Product type: Reference compound1
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