IOX4 is a selective HIF prolyl-hydroxylase 2 (PHD2) inhibitor with an IC50 value of 1.6 nM, induces HIFalpha in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2[1].
Molecular Weight:
328.33
Purity:
99.96
CAS Number:
[1154097-71-8]
Formula:
C15H16N6O3
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
MCE Product type: Reference compound1
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