(R)-KMH-233 is the isomer of KMH-233 (HY-120139), and can be used as an experimental control. KMH-233, a potent, reversible and selective l-type amino acid transporter 1 (LAT1) inhibitor, inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 µM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 µM)[1].
Molecular Weight:
587.58
CAS Number:
[2994330-89-9]
Formula:
C32H25N7O5
Target:
ASCT
Application Notes:
MCE Product type: Reference compound1
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