GS-493 is a selective protein tyrosine phosphatase SHP2 (PTPN11) inhibitor with an IC50 of 71 nM. GS-493 is 29- and 45-fold more active toward SHP2 than related SHP1 and PTP1B. GS-493 blocks cellular motility and growth of cancer cells. Antitumor activity[1].
Molecular Weight:
510.44
CAS Number:
[1710337-31-7]
Formula:
C21H14N6O8S
Target:
Phosphatase,SHP1,SHP2
Application Notes:
MCE Product type: Reference compound
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