LP-922761 is a potent, selective and orally active adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50s of 4.8 nM and 7.6 nM in enzyme and cell assays, respectively. LP-922761 also inhibits BMP-2-inducible protein kinase (BIKE) with an IC50 of 24 nM. LP-922761 exhibits no significant activity at cyclin G-associated kinase (GAK), opioid, adrenergic alpha2 or GABAa receptors[1].
Molecular Weight:
410.47
Purity:
99.73
CAS Number:
[1454808-95-7]
Formula:
C21H26N6O3
Target:
AAK1
Application Notes:
MCE Product type: Reference compound
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