GSK-340 is a BET inhibitor with high affinity and significant selectivity for BD2 from BRD4 with a pIC50 of 7.2. GSK-340 inhibits MCP-1 release in Lipopolysaccharide (HY-D1056) treated PBMCs and whole blood with the pIC50 of 7.4 and 6.0, respectively. GSK-340 has immunomodulatory activity[1].
Molecular Weight:
417.54
CAS Number:
[2222509-79-5]
Formula:
C26H31N3O2
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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