Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species[1][2][3][4].
Molecular Weight:
365.39
Purity:
99
CAS Number:
[192564-13-9]
Formula:
C15H12KN5O4
Target:
Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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