GGTI-297 is a geranylgeranyl transferase I (GGTase-1) inhibitor with IC50 values of 56 nM and 203 nM for GGTase-1 and fanesyl transferase (FTase), respectively. GGTI-297 inhibits the processing of the geranylgeranylated protein Rap1A without affecting the farnesylated protein H-Ras[1][2].
Molecular Weight:
465.61
CAS Number:
[181045-83-0]
Formula:
C26H31N3O3S
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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