KY-226 is a potent, selective, orally active and allosteric protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 0.25 µM, and without PPARgamma agonist activity. KY-226 exerts anti-diabetic and anti-obesity effects by enhancing insulin and leptin signaling, respectively. KY-226 also protects neurons from cerebral ischemic injury[1][2].
Molecular Weight:
481.67
Purity:
98.42
CAS Number:
[1621673-53-7]
Formula:
C27H31NO3S2
Target:
Phosphatase
Application Notes:
MCE Product type: Reference compound
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