2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17beta-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].
Molecular Weight:
302.41
Purity:
99.82
CAS Number:
[362-07-2]
Formula:
C19H26O3
Target:
Apoptosis,Autophagy,Endogenous Metabolite,Microtubule/Tubulin,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
* VAT and and shipping costs not included. Errors and price changes excepted
