2-Methoxyestradiol (Standard) is the analytical standard of 2-Methoxyestradiol. This product is intended for research and analytical applications. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17beta-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].
Molecular Weight:
302.41
CAS Number:
[362-07-2]
Formula:
C19H26O3
Target:
Apoptosis,Autophagy,Endogenous Metabolite,Microtubule/Tubulin,Reactive Oxygen Species (ROS),Reference Standards
Application Notes:
MCE Product type: Reference Standards
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