2-Methoxyestradiol-d5 is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17beta-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6][7].
Molecular Weight:
307.44
Purity:
98.67
CAS Number:
[358731-34-7]
Formula:
C19H21D5O3
Target:
Apoptosis,Autophagy,Endogenous Metabolite,Isotope-Labeled Compounds,Microtubule/Tubulin,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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