AMG-208 is an orally active c-Met/RON dual selective inhibitor with an IC50 of 9 nM for c-Met. AMG-208 is a CYP3A4 inhibitor with an IC50 of 32 µM. AMG-208 has anti-cancer activity[1][2][3].
Molecular Weight:
383.40
Purity:
99.86
CAS Number:
[1002304-34-8]
Formula:
C22H17N5O2
Target:
c-Met/HGFR,Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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