MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C, with a Kd of 4.1 µM. MB710 shows anticancer activity in p53-Y220C cell lines[1].
Molecular Weight:
457.29
Purity:
98.81
CAS Number:
[2230044-57-0]
Formula:
C16H16IN3O3S
Target:
MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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