UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity[1].
Molecular Weight:
441.56
Purity:
98
CAS Number:
[299420-83-0]
Formula:
C26H35NO5
Target:
Apoptosis,STAT,TET Protein
Application Notes:
MCE Product type: Reference compound
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