AB1 is a highly selective S1P2 receptor antagonist (IC50=3.5 nM). AB1 inhibits sphingosine-1-phosphate (S1P) signaling, suppressing tumor cell migration, angiogenesis, and profibrotic mediator CTGF expression while inducing apoptosis. AB1 is promising for research of solid tumors[1].
Molecular Weight:
434.32
CAS Number:
[1463912-49-3]
Formula:
C19H21Cl2N7O
Target:
Apoptosis,LPL Receptor
Application Notes:
MCE Product type: Reference compound1
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