SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 induces the transformation of bladder cancer cells from autophagy to apoptosis[1][2][3].
Molecular Weight:
220.23
Purity:
99.73
CAS Number:
[129-56-6]
Formula:
C14H8N2O
Target:
Apoptosis,Autophagy,Ferroptosis,JNK
Application Notes:
MCE Product type: Reference compound
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