Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C, with an IC50 of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC50 of 1.5 µM and displaces Bax from Bcl-XL. Chelerythrine chloride induces apoptosis and autophagy.
Molecular Weight:
383.82
Purity:
99.11
CAS Number:
[3895-92-9]
Formula:
C21H18ClNO4
Target:
Apoptosis,Autophagy,Bcl-2 Family,PKC
Application Notes:
MCE Product type: Natural Products
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