Raxofelast (IRFI-016) is an antioxidant agent in various models of ischemia-reperfusion injury. Raxofelast has antiproliferative activity in H2O2-stimulated rat aortic smooth muscle cells. Raxofelast attenuates the activation of mitogen-activating protein kinase (MAPK), ERK kinase 1, 2 (MEK1,2) and protein kinase C (PKC) without affecting Ras expression[1].
Molecular Weight:
278.30
CAS Number:
[128232-14-4]
Formula:
C15H18O5
Target:
ERK,p38 MAPK,PKC
Application Notes:
MCE Product type: Reference compound1
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