5-LOX-IN-6 (compound 11a) is a direct and reversible inhibitor of 5-lipoxygenase (5-LO). 5-LOX-IN-6 inhibits 5-LO activity in human neutrophils and recombinant human 5-LO with IC50 values of 0.23 and 0.086 µM, respectively. 5-LOX-IN-6 prevents leukotriene biosynthesis. 5-LOX-IN-6 can be used for inflammatory and allergic disorders research[1].
Molecular Weight:
379.84
CAS Number:
[1159576-98-3]
Formula:
C22H18ClNO3
Target:
Leukotriene Receptor,Lipoxygenase
Application Notes:
MCE Product type: Reference compound1
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