JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator) with nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50 = 7.71)[1].
Molecular Weight:
414.47
Purity:
98.77
CAS Number:
[1254980-38-5]
Formula:
C23H25F3N4
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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