RS 49676 is an N-substituted imidazole compound that exhibits strong in vitro activity against endogenous amoebae (ED50 < 0.1 ng/mL), but is ineffective against exogenous amoebae (epimastigotes). In vivo, RS 49676 (100 mg/kg/d, sc, 2 times) can prolong the average survival time of mice infected with Trypanosoma cruzi to more than 11 weeks.
Molecular Weight:
485.96
CAS Number:
[111962-89-1]
Formula:
C25H28ClN3O5
Target:
Parasite
Application Notes:
MCE Product type: Reference compound
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