Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].
Molecular Weight:
489.92
Purity:
99.85
CAS Number:
[918504-65-1]
Formula:
C23H18ClF2N3O3S
Target:
Autophagy,Raf
Application Notes:
MCE Product type: Reference compound
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