Sibiriline, CAS [[1346526-26-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-120600
Supplier Catalog Number:
HY-120600
Alternative Catalog Number:
MCE-HY-120600-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Sibiriline is a specific competitive inhibitor of RIPK1 that targets the RIPK1 ATP-binding site and locks it in an inactive conformation. Sibiriline inhibits TNF-induced RIPK1-dependent necroptosis and RIPK1-dependent apoptosis, but does not protect cells from caspase-dependent apoptosis. Sibiriline protects mice from concanavalin A-induced hepatitis and has the potential to inhibit immune-dependent hepatitis.[1].
Molecular Weight:
210.23
CAS Number:
[1346526-26-8]
Formula:
C13H10N2O
Target:
Apoptosis,Necroptosis,RIP kinase
Application Notes:
MCE Product type: Reference compound
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