BMS-243117 is a potent, and selective benzothiazole based p56Lck inhibitor with an IC50 of 4 nM. BMS-243117 inhibits anti-CD3/anti-CD28 induced PBL (human peripheral blood T-cells) proliferation with an IC50 of 1.1 µM. BMS-243117 binds in an extended conformation to the ATP-binding site of Lck[1].
Molecular Weight:
416.92
CAS Number:
[225521-80-2]
Formula:
C20H21ClN4O2S
Target:
Src
Application Notes:
MCE Product type: Reference compound
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