BMS-250749 is a topoisomerase I (Top I) inhibitor of the fluoroglycosyl-3,9-difluoroindolecarbazole class. BMS-250749 exhibits potent cytotoxicity and selectivity, and shows curative antitumor activity against Lewis lung cancer. BMS-250749 exhibits broad-spectrum antitumor activity superior to CPT-11 in certain preclinical xenograft models.[1].
Molecular Weight:
525.43
CAS Number:
[406913-72-2]
Formula:
C26H18F3N3O6
Target:
Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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