LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3].
Molecular Weight:
479.40
Purity:
99.75
CAS Number:
[1435934-00-1]
Formula:
C25H24Cl2N6
Target:
Organoid,TGF-beta Receptor
Application Notes:
Reference compound
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