VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM) (binds to the MPEP (HY-14609A) site), with an EC50 of 1.6 µM. VU0364289 can reverse amphetamine-induced hyperlocomotion in a dose-dependent manner, which can be used for schizophrenia and other psychiatric research[1][2][3].
Molecular Weight:
335.40
Purity:
99.52
CAS Number:
[1242443-29-3]
Formula:
C20H21N3O2
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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