BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases[1].
Molecular Weight:
512.89
Purity:
99.36
CAS Number:
[1025720-94-8]
Formula:
C25H19ClF2N4O4
Target:
c-Met/HGFR,TAM Receptor
Application Notes:
MCE Product type: Reference compound
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