LB42908 is a potent, selective and orally active farnesyltransferase inhibitor. LB42908 inhibits farnesylation of H-Ras, K-Ras with IC50 values of 0.9 nM, 2.4 nM for H-Ras, K-Ras, respectively. LB42908 shows antiproliferative activity. LB42908 shows antitumor activity[1].
Molecular Weight:
533.62
CAS Number:
[226927-89-5]
Formula:
C32H31N5O3
Target:
Farnesyl Transferase
Application Notes:
MCE Product type: Reference compound
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