GSK729 is a THPP inhibitor with the activity of inhibiting EchA6 and inhibiting Mycobacterium tuberculosis. GSK729 can selectively pull down EchA6 in a stereospecific manner, inhibit its activity, inhibit fatty acid synthesis of Mycobacterium tuberculosis, and has a bactericidal effect in a mouse chronic tuberculosis infection model.
Molecular Weight:
339.31
CAS Number:
[1403602-92-5]
Formula:
C16H16F3N3O2
Target:
Bacterial
Application Notes:
Reference compound
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