CP-481715 is a potent, reversible and selective CCR1 antagonist with a Kd of 9.2 nM for human CCR1. CP-481715 is >100-fold selective for CCR1 as compared with a panel of G-protein-coupled receptors including related chemokine receptors. CP-481715 has the potential for rheumatoid arthritis and other inflammatory diseases research[1].
Molecular Weight:
482.55
CAS Number:
[212790-31-3]
Formula:
C26H31FN4O4
Target:
CCR
Application Notes:
Reference compound
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