A2AAR/hMAO-B-IN-1 (compoudn 17) is a non-xanthine dual-target inhibitor targeting the A2A adenosine receptor (A2AAR) (IC50: 34.9 nM) andMAO-B (Ki: 39.5 nM, human). A2AAR/hMAO-B-IN-1 inhibits A2AAR-induced cAMP accumulation and exhibits competitive, reversible inhibition of MAO-B. A2AAR/hMAO-B-IN-1 can be used in the study of neurodegenerative diseases such as Parkinsons disease (PD)[1].
Molecular Weight:
324.40
Purity:
99
CAS Number:
[1439488-21-7]
Formula:
C18H16N2O2S
Target:
Adenosine Receptor,Monoamine Oxidase
Application Notes:
MCE Product type: Reference compound
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