Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-alpha release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1].
Molecular Weight:
460.50
Purity:
99.87
CAS Number:
[608141-41-9]
Formula:
C22H24N2O7S
Target:
Apoptosis,Phosphodiesterase (PDE),TNF Receptor
Application Notes:
MCE Product type: Reference compound
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