1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 µM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.
Molecular Weight:
444.25
Purity:
98
CAS Number:
[200716-66-1]
Formula:
C12H20Br2N4S2
Target:
NO Synthase
Application Notes:
MCE Product type: Reference compound
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