Darigabat, CAS [[1614245-70-3]]

Product Overview

• Article Name: Darigabat, CAS [[1614245-70-3]]
• Biozol Catalog Number: MCE-HY-120874
• Supplier Catalog Number: HY-120874
• Alternative Catalog Number: MCE-HY-120874-10MMX1ML,MCE-HY-120874-25MG,MCE-HY-120874-100MG,MCE-HY-120874-5MG,MCE-HY-120874-50MG,MCE-HY-120874-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PF-06372865, CVL-865

Product Description

Darigabat (PF-06372865) is an orally active, alpha2/alpha3/alpha5 subtype-selective GABAA positive allosteric modulator (PAM). Darigabat is a high affinity ligand at GABAA receptors containing alpha1/alpha2/alpha3/alpha5 subunits (Kis of 2.9 nM, 21 nM, 134 nM for alpha2, alpha1 PAM, alpha2 PAM, respectively), with low affinity for alpha4/alpha6 subunits. Darigabat can across the blood-brain barrier (BBB). Darigabat has anxiolytic activity and has the potential for epilepsy[1].

Product Properties

• Molecular Weight: 440.49
• Purity: 99.29
• CAS Number: [1614245-70-3]
• Formula: C22H21FN4O3S
• Target: GABA Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound