TrxR1-IN-B19 (GO-Y015) (Compound B19) is a Curcumin (HY-N0005) derivative and colvalent TrxR1 inhibitor. TrxR1-IN-B19 inhibits TrxR1 enzyme activity to elevate oxidative stress, and then induce ROS-mediated ER Stress and mitochondrial dysfunction, subsequently resulting in cell cycle arrest and apoptosis[1].
Molecular Weight:
354.40
CAS Number:
[170950-29-5]
Formula:
C21H22O5
Target:
Apoptosis,TrxR
Application Notes:
MCE Product type: Reference compound1
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