Biguanide is an orally active antihyperglycemic agent. Biguanide inhibits mitochondrial ATP production, activates the LKB1-AMPK signaling pathway, and damages the energy homeostasis. Biguanide enhances insulin-receptor activation and downstream signaling. Biguanide exhibits potential in ameliorating the type 2 diabetes and the insulin-associated cancers[1].
Molecular Weight:
101.11
Purity:
98.07
CAS Number:
[56-03-1]
Formula:
C2H7N5
Target:
AMPK,Insulin Receptor,Mitochondrial Metabolism
Application Notes:
MCE Product type: Reference compound
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