Eggmanone (EGM1) is a potent and selective phosphodiesterase 4 (PDE4) antagonist with an IC50 of 72 nM for PDE4D3. Eggmanone shows approximately 40- to 50-fold selective for PDE4D3 over other PDEs. Eggmanone exerts its Hh-inhibitory effects through selective antagonism of PDE4, leading to protein kinase A activation and subsequent Hh blockade[1].
Molecular Weight:
416.58
Purity:
95.31
CAS Number:
[505068-32-6]
Formula:
C20H20N2O2S3
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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