AZ1729 is a potent free fatty acid 2 receptor (FFA2) activator, acting as a direct allosteric agonist and as a positive allosteric modulator. AZ1729 increases the activity of the endogenously produced short chain fatty acid propionate in Gi-mediated pathways, but not at those transduced by Gq/G11. AZ1729 induces inhibition of isoproterenol-induced lipolysis in mouse adipocytes. AZ1729 also can Induce migration of human neutrophils. AZ1729 can be used for researching the signaling pathways of the physiological roles of FFA2[1].
Molecular Weight:
369.42
Purity:
99.8
CAS Number:
[2016864-46-1]
Formula:
C18H16FN5OS
Target:
Free Fatty Acid Receptor
Application Notes:
MCE Product type: Reference compound1
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